Description
Il11ra1, also known as interleukin-11 receptor subunit alpha, is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. It can utilize IL6ST for initiating signal transmission. It is expressed in a number of cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Recombinant rat Il11ra1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques